Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2268036..2268307 Replicon chromosome
Accession NZ_CP076237
Organism Escherichia coli O157:H7 strain 146N4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2268166..2268269 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2268036..2268307 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKN67_RS11360 2264591..2265253 - 663 WP_000944243.1 exodeoxyribonuclease X -
JKN67_RS11365 2265277..2265933 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
JKN67_RS11370 2266035..2266265 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JKN67_RS11375 2266404..2266778 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JKN67_RS11380 2266782..2267654 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JKN67_RS11385 2267667..2268008 + 342 WP_000976483.1 YebY family protein -
- 2268036..2268307 - 272 - - Antitoxin
- 2268166..2268269 + 104 - - Toxin
JKN67_RS11390 2268404..2269060 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JKN67_RS11395 2269061..2269252 - 192 WP_001296140.1 YebW family protein -
JKN67_RS11400 2269357..2269593 - 237 WP_001295499.1 YebV family protein -
JKN67_RS11405 2269711..2271150 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T204870 NZ_CP076237:2268166-2268269 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT204870 NZ_CP076237:c2268307-2268036 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References