Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2275398..2275669 Replicon chromosome
Accession NZ_CP076235
Organism Escherichia coli O157:H7 strain 9.1_Anguil

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2275528..2275631 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2275398..2275669 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKN68_RS11475 2271953..2272615 - 663 WP_000944244.1 exodeoxyribonuclease X -
JKN68_RS11480 2272639..2273295 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
JKN68_RS11485 2273397..2273627 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JKN68_RS11490 2273766..2274140 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JKN68_RS11495 2274144..2275016 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JKN68_RS11500 2275029..2275370 + 342 WP_000976483.1 YebY family protein -
- 2275398..2275669 - 272 - - Antitoxin
- 2275528..2275631 + 104 - - Toxin
JKN68_RS11505 2275766..2276422 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JKN68_RS11510 2276423..2276614 - 192 WP_001296140.1 YebW family protein -
JKN68_RS11515 2276719..2276955 - 237 WP_001295499.1 YebV family protein -
JKN68_RS11520 2277073..2278512 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T204837 NZ_CP076235:2275528-2275631 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT204837 NZ_CP076235:c2275669-2275398 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References