Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 964676..965348 Replicon chromosome
Accession NZ_CP075169
Organism Sodalis ligni strain dw23

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GTU79_RS04475 Protein ID WP_132923342.1
Coordinates 964923..965348 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GTU79_RS04470 Protein ID WP_132923343.1
Coordinates 964676..964942 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GTU79_RS04445 (GTU79_04445) 959993..960436 - 444 WP_203522751.1 PTS sugar transporter subunit IIA -
GTU79_RS04450 (GTU79_04450) 960662..961315 - 654 WP_203522750.1 AAA family ATPase -
GTU79_RS04455 (GTU79_04455) 961308..962252 - 945 WP_203522749.1 tagatose-bisphosphate aldolase -
GTU79_RS04460 (GTU79_04460) 962492..963445 + 954 WP_243701591.1 sugar-binding domain-containing protein -
GTU79_RS04465 (GTU79_04465) 963473..964459 - 987 WP_132923344.1 tRNA-modifying protein YgfZ -
GTU79_RS04470 (GTU79_04470) 964676..964942 + 267 WP_132923343.1 FAD assembly factor SdhE Antitoxin
GTU79_RS04475 (GTU79_04475) 964923..965348 + 426 WP_132923342.1 protein YgfX Toxin
GTU79_RS04480 (GTU79_04480) 965353..965871 - 519 WP_132923341.1 flavodoxin FldB -
GTU79_RS04485 (GTU79_04485) 965973..966872 + 900 WP_132923340.1 site-specific tyrosine recombinase XerD -
GTU79_RS04490 (GTU79_04490) 967007..967723 + 717 WP_203522747.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
GTU79_RS04495 (GTU79_04495) 967737..969467 + 1731 WP_203522746.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16586.58 Da        Isoelectric Point: 11.8737

>T203301 WP_132923342.1 NZ_CP075169:964923-965348 [Sodalis ligni]
VALWRCDVRVSWRTQIFSLVIHGILTLLILLSPWPENYGLVWVTLITLVVFECIRSQRNIMACRGELVLQSGLHLRWHNK
DWLIRGTPWMLKSGILISLRQVGGRRTRKLWLAADSMDQREWRSLRQALLHAASVQQRHDR

Download         Length: 426 bp

>T203301 NZ_CP099910:298428-298955 [Escherichia albertii]
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTCGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTGGTTCGTCAACATCGCAATAAAATTTTGCGAGCGTATATCCTTTGCCGCAACACTC
CAGAACGTCAGGTCCTGGGATATTACACATTATCCGGCAGTTGTTTTGAACGAGCCGCACTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTCACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGATTGCTCATGCCATGAAAGTCGTCTGGTCAGCCTCATTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCTCTGAATGAAAAAGCCCATACGTTTTATCAGTCGCTGGGCTTTATCCCATTGGTTGGAGAAAACGAAAATGCGTTA
TTTTTCCCAACTAAATCCATTGAACTGCTTTTTACACAGAGCGATTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10370.88 Da        Isoelectric Point: 4.8186

>AT203301 WP_132923343.1 NZ_CP075169:964676-964942 [Sodalis ligni]
MDIDNRARIHWACRRGMRELDISIMPFFEYDFDTLSDEDKGLFVRLLECDDPDLFNWLMNHGEPQDSGLKKMINLIQTRN
KARGPLAL

Download         Length: 267 bp

>AT203301 NZ_CP099910:298155-298421 [Escherichia albertii]
ATGTCTGCTGTTAAAAAGCAGCGTATCGATCTGCGTTTAACTGACGATGACAAAAGTATGATTGAGGAAGCGGCAGCGAT
ATCTAATCAATCCGTCAGCCAATTTATGTTGAACAGCGCTTCGCAGCGAGCTGCGGAAGTGATTGAACAGCATCGGCGGA
TGATTCTCAATGAGGAATCCTGGACGCGGGTGATGGATGCGCTGAGTAATCCACCGTCACCAGGTGAAAAGTTAAAACGT
GCGGCAAAACGTCTTCAGGGAATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References