Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2015513..2015667 Replicon chromosome
Accession NZ_CP075134
Organism Salmonella enterica subsp. enterica serovar Saintpaul strain CFSAN044909

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2015551..2015654 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2015513..2015667 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7S31_RS09630 2011937..2012635 - 699 WP_000944278.1 exodeoxyribonuclease X -
A7S31_RS09635 2012659..2013315 - 657 WP_001524390.1 carbon-nitrogen hydrolase family protein -
A7S31_RS09640 2013423..2013653 - 231 WP_000856224.1 DNA polymerase III subunit theta -
A7S31_RS09645 2013791..2014165 + 375 WP_000168393.1 CopC domain-containing protein YobA -
A7S31_RS09650 2014166..2015041 + 876 WP_000979694.1 copper homeostasis membrane protein CopD -
A7S31_RS09655 2015058..2015411 + 354 WP_000722368.1 YebY family protein -
- 2015513..2015667 - 155 - - Antitoxin
- 2015551..2015654 + 104 - - Toxin
A7S31_RS09660 2015785..2016863 - 1079 Protein_1894 phage integrase Arm DNA-binding domain-containing protein -
A7S31_RS09665 2016896..2018047 - 1152 Protein_1895 PD-(D/E)XK nuclease-like domain-containing protein -
A7S31_RS09670 2018036..2018227 + 192 Protein_1896 glycoside hydrolase family 19 protein -
A7S31_RS09675 2018281..2018814 + 534 WP_001050883.1 DUF2514 domain-containing protein -
A7S31_RS09680 2019071..2019238 - 168 WP_000789530.1 lytic enzyme -
A7S31_RS09685 2019303..2019491 - 189 WP_001525026.1 hypothetical protein -
A7S31_RS09690 2019546..2020037 + 492 WP_001525042.1 DUF1441 family protein -
A7S31_RS09695 2020024..2020591 + 568 Protein_1901 phage terminase large subunit family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1993642..2051216 57574


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T203177 NZ_CP075134:2015551-2015654 [Salmonella enterica subsp. enterica serovar Saintpaul]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 155 bp

>AT203177 NZ_CP075134:c2015667-2015513 [Salmonella enterica subsp. enterica serovar Saintpaul]
TTTTAATCTAAATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGC
TAAAAGTTGGCATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References