Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2102594..2102737 Replicon chromosome
Accession NZ_CP075125
Organism Salmonella enterica strain CFSAN044945

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2102632..2102735 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2102594..2102737 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7S67_RS10045 2099019..2099717 - 699 WP_000944280.1 exodeoxyribonuclease X -
A7S67_RS10050 2099741..2100397 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
A7S67_RS10055 2100504..2100734 - 231 WP_000856225.1 DNA polymerase III subunit theta -
A7S67_RS10060 2100872..2101246 + 375 WP_000168393.1 CopC domain-containing protein YobA -
A7S67_RS10065 2101247..2102122 + 876 WP_000979696.1 copper homeostasis membrane protein CopD -
A7S67_RS10070 2102139..2102492 + 354 WP_000722368.1 YebY family protein -
- 2102594..2102737 - 144 - - Antitoxin
- 2102632..2102735 + 104 - - Toxin
A7S67_RS10075 2102875..2103954 - 1080 Protein_1980 phage integrase Arm DNA-binding domain-containing protein -
A7S67_RS10080 2103987..2105135 - 1149 Protein_1981 PD-(D/E)XK nuclease-like domain-containing protein -
A7S67_RS10085 2105127..2105375 + 249 Protein_1982 glycoside hydrolase family 19 protein -
A7S67_RS10090 2105372..2105905 + 534 WP_001529209.1 DUF2514 domain-containing protein -
A7S67_RS10095 2106174..2106341 - 168 WP_000789530.1 lytic enzyme -
A7S67_RS10100 2106644..2107135 + 492 WP_001629197.1 DUF1441 family protein -
A7S67_RS10105 2107227..2107689 + 463 Protein_1986 phage terminase large subunit family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2096931..2135742 38811


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T203081 NZ_CP075125:2102632-2102735 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT203081 NZ_CP075125:c2102737-2102594 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References