Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1944617..1944762 Replicon chromosome
Accession NZ_CP075108
Organism Salmonella enterica strain CFSAN060808

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1944657..1944760 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1944617..1944762 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CIC23_RS09250 1941043..1941741 - 699 WP_000944285.1 exodeoxyribonuclease X -
CIC23_RS09255 1941765..1942421 - 657 WP_000100257.1 carbon-nitrogen hydrolase family protein -
CIC23_RS09260 1942529..1942759 - 231 WP_000856224.1 DNA polymerase III subunit theta -
CIC23_RS09265 1942897..1943271 + 375 WP_000168393.1 CopC domain-containing protein YobA -
CIC23_RS09270 1943272..1944147 + 876 WP_072103328.1 copper homeostasis membrane protein CopD -
CIC23_RS09275 1944164..1944517 + 354 WP_023261262.1 YebY family protein -
- 1944617..1944762 - 146 - - Antitoxin
- 1944657..1944760 + 104 - - Toxin
CIC23_RS09280 1944890..1945969 - 1080 WP_000087646.1 phage integrase Arm DNA-binding domain-containing protein -
CIC23_RS09285 1946002..1947153 - 1152 Protein_1822 PD-(D/E)XK nuclease-like domain-containing protein -
CIC23_RS09290 1947142..1947333 + 192 Protein_1823 glycoside hydrolase family 19 protein -
CIC23_RS09295 1947387..1947920 + 534 WP_001050883.1 DUF2514 domain-containing protein -
CIC23_RS09300 1948177..1948344 - 168 WP_000789530.1 lytic enzyme -
CIC23_RS09305 1948409..1948597 - 189 WP_001532317.1 hypothetical protein -
CIC23_RS09310 1948652..1948912 + 261 Protein_1827 DUF1441 family protein -
CIC23_RS22480 1948914..1949129 + 216 Protein_1828 shikimate transporter -
CIC23_RS09315 1949139..1949426 + 288 Protein_1829 macro domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1922748..1977850 55102


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T202846 NZ_CP075108:1944657-1944760 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT202846 NZ_CP075108:c1944762-1944617 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References