Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1232841..1233430 Replicon chromosome
Accession NZ_CP074076
Organism Xanthomonas oryzae strain AH28

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag KCI36_RS05810 Protein ID WP_011260747.1
Coordinates 1232841..1233122 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KCI36_RS05815 Protein ID WP_011260746.1
Coordinates 1233140..1233430 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KCI36_RS05805 (KCI36_05805) 1230494..1232746 + 2253 WP_011409750.1 exodeoxyribonuclease V subunit alpha -
KCI36_RS05810 (KCI36_05810) 1232841..1233122 + 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KCI36_RS05815 (KCI36_05815) 1233140..1233430 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
KCI36_RS05820 (KCI36_05820) 1234368..1235762 + 1395 WP_027703652.1 type III secretion system effector XopQ -
KCI36_RS23475 1235865..1236052 - 188 Protein_1110 hypothetical protein -
KCI36_RS05825 (KCI36_05825) 1236212..1236544 - 333 WP_011260743.1 hypothetical protein -
KCI36_RS05830 (KCI36_05830) 1236799..1237125 + 327 WP_228329596.1 hypothetical protein -
KCI36_RS05835 (KCI36_05835) 1237253..1237675 + 423 WP_042465811.1 PAAR domain-containing protein -
KCI36_RS05840 (KCI36_05840) 1237678..1238286 + 609 WP_011409746.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11070.83 Da        Isoelectric Point: 10.2139

>T201336 WP_011260747.1 NZ_CP074076:1232841-1233122 [Xanthomonas oryzae]
MIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T201336 NZ_CP098338:c4817714-4817181 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT201336 WP_011260746.1 NZ_CP074076:1233140-1233430 [Xanthomonas oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT201336 NZ_CP098338:c4817991-4817725 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References