Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2357236..2357507 Replicon chromosome
Accession NZ_CP074007
Organism Escherichia coli strain PD4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2357366..2357469 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2357236..2357507 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU74_RS11285 2353792..2354454 - 663 WP_000944256.1 exodeoxyribonuclease X -
KFU74_RS11290 2354478..2355134 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KFU74_RS11295 2355236..2355466 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU74_RS11300 2355605..2355979 + 375 WP_000255065.1 CopC domain-containing protein YobA -
KFU74_RS11305 2355983..2356855 + 873 WP_000879297.1 copper homeostasis membrane protein CopD -
KFU74_RS11310 2356868..2357209 + 342 WP_000976472.1 YebY family protein -
- 2357236..2357507 - 272 - - Antitoxin
- 2357366..2357469 + 104 - - Toxin
KFU74_RS11315 2357604..2358260 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
KFU74_RS11320 2358261..2358452 - 192 WP_001296140.1 YebW family protein -
KFU74_RS11325 2358557..2358793 - 237 WP_001295499.1 YebV family protein -
KFU74_RS11330 2358911..2360350 - 1440 WP_112916870.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201056 NZ_CP074007:2357366-2357469 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT201056 NZ_CP074007:c2357507-2357236 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References