Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1996118..1996389 Replicon chromosome
Accession NZ_CP074001
Organism Escherichia coli strain PM4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1996248..1996351 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1996118..1996389 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU80_RS09680 1992673..1993335 - 663 WP_000944258.1 exodeoxyribonuclease X -
KFU80_RS09685 1993359..1994015 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KFU80_RS09690 1994117..1994347 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU80_RS09695 1994486..1994860 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KFU80_RS09700 1994864..1995736 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
KFU80_RS09705 1995749..1996090 + 342 WP_000976472.1 YebY family protein -
- 1996118..1996389 - 272 - - Antitoxin
- 1996248..1996351 + 104 - - Toxin
KFU80_RS09710 1996486..1997142 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
KFU80_RS09715 1997143..1997334 - 192 WP_001338167.1 YebW family protein -
KFU80_RS09720 1997439..1997675 - 237 WP_001338166.1 YebV family protein -
KFU80_RS09725 1997793..1999232 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T201013 NZ_CP074001:1996248-1996351 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT201013 NZ_CP074001:c1996389-1996118 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References