Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2038502..2038773 Replicon chromosome
Accession NZ_CP073958
Organism Escherichia coli strain MB46

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2038632..2038735 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2038502..2038773 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU88_RS10020 2035057..2035719 - 663 WP_000944258.1 exodeoxyribonuclease X -
KFU88_RS10025 2035743..2036399 - 657 WP_001752600.1 carbon-nitrogen hydrolase family protein YobB -
KFU88_RS10030 2036501..2036731 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU88_RS10035 2036870..2037244 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KFU88_RS10040 2037248..2038120 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
KFU88_RS10045 2038133..2038474 + 342 WP_000976472.1 YebY family protein -
- 2038502..2038773 - 272 - - Antitoxin
- 2038632..2038735 + 104 - - Toxin
KFU88_RS10050 2038870..2039526 + 657 WP_001752599.1 protein-serine/threonine phosphatase -
KFU88_RS10055 2039527..2039718 - 192 WP_001338167.1 YebW family protein -
KFU88_RS10060 2039823..2040059 - 237 WP_001338166.1 YebV family protein -
KFU88_RS10065 2040177..2041616 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T200809 NZ_CP073958:2038632-2038735 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT200809 NZ_CP073958:c2038773-2038502 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References