Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1943960..1944231 Replicon chromosome
Accession NZ_CP073943
Organism Escherichia coli strain MB52

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1944090..1944193 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1943960..1944231 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU89_RS09275 1940515..1941177 - 663 WP_000944256.1 exodeoxyribonuclease X -
KFU89_RS09280 1941201..1941857 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
KFU89_RS09285 1941959..1942189 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU89_RS09290 1942328..1942702 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KFU89_RS09295 1942706..1943578 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
KFU89_RS09300 1943591..1943932 + 342 WP_000976476.1 YebY family protein -
- 1943960..1944231 - 272 - - Antitoxin
- 1944090..1944193 + 104 - - Toxin
KFU89_RS09305 1944328..1944984 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
KFU89_RS09310 1944985..1945176 - 192 WP_001296140.1 YebW family protein -
KFU89_RS09315 1945281..1945517 - 237 WP_001295499.1 YebV family protein -
KFU89_RS09320 1945635..1947074 - 1440 WP_024174420.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T200701 NZ_CP073943:1944090-1944193 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT200701 NZ_CP073943:c1944231-1943960 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References