Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2127000..2127271 Replicon chromosome
Accession NZ_CP073926
Organism Escherichia coli strain MB98

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2127130..2127233 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2127000..2127271 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFU77_RS10225 2123555..2124217 - 663 WP_000944256.1 exodeoxyribonuclease X -
KFU77_RS10230 2124241..2124897 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KFU77_RS10235 2124999..2125229 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KFU77_RS10240 2125368..2125742 + 375 WP_000204699.1 CopC domain-containing protein YobA -
KFU77_RS10245 2125746..2126618 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
KFU77_RS10250 2126631..2126972 + 342 WP_000976492.1 YebY family protein -
- 2127000..2127271 - 272 - - Antitoxin
- 2127130..2127233 + 104 - - Toxin
KFU77_RS10255 2127368..2128024 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
KFU77_RS10260 2128025..2128216 - 192 WP_001296140.1 YebW family protein -
KFU77_RS10265 2128321..2128557 - 237 WP_001295499.1 YebV family protein -
KFU77_RS10270 2128675..2130114 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T200575 NZ_CP073926:2127130-2127233 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT200575 NZ_CP073926:c2127271-2127000 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References