Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1913661..1913806 Replicon chromosome
Accession NZ_CP073906
Organism Klebsiella pneumoniae strain HK31

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1913697..1913799 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1913661..1913806 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFK82_RS09275 1908791..1910851 + 2061 WP_004151449.1 oligopeptidase B -
KFK82_RS09280 1910855..1911514 - 660 WP_002911407.1 exodeoxyribonuclease X -
KFK82_RS09285 1911593..1911823 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KFK82_RS09290 1911936..1912310 + 375 WP_039819395.1 CopC domain-containing protein YobA -
KFK82_RS09295 1912314..1913183 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KFK82_RS09300 1913200..1913538 + 339 WP_002911404.1 YebY family protein -
- 1913661..1913806 - 146 - - Antitoxin
- 1913697..1913799 + 103 - - Toxin
KFK82_RS09305 1914175..1914318 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
KFK82_RS09310 1914423..1915391 - 969 WP_014907334.1 VirK/YbjX family protein -
KFK82_RS09315 1915548..1916201 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
KFK82_RS09320 1916198..1916389 - 192 WP_002911395.1 YebW family protein -
KFK82_RS09325 1916487..1916726 - 240 WP_002911393.1 YebV family protein -
KFK82_RS09330 1916842..1918275 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T200501 NZ_CP073906:1913697-1913799 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT200501 NZ_CP073906:c1913806-1913661 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References