Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3273042..3273189 Replicon chromosome
Accession NZ_CP073791
Organism Klebsiella pneumoniae isolate KP_NORM_BLD_2010_71621

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3273046..3273148 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3273042..3273189 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFO61_RS16000 (KFO61_15995) 3268570..3270003 + 1434 WP_064183816.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KFO61_RS16005 (KFO61_16000) 3270120..3270359 + 240 WP_002911393.1 YebV family protein -
KFO61_RS16010 (KFO61_16005) 3270457..3270648 + 192 WP_002911395.1 YebW family protein -
KFO61_RS16015 (KFO61_16010) 3270645..3271298 - 654 WP_114446962.1 protein-serine/threonine phosphatase -
KFO61_RS16020 (KFO61_16015) 3271455..3272423 + 969 WP_142737047.1 VirK/YbjX family protein -
KFO61_RS16025 (KFO61_16020) 3272524..3272667 + 144 WP_032425946.1 Ecr family regulatory small membrane protein -
- 3273042..3273189 + 148 - - Antitoxin
- 3273046..3273148 - 103 - - Toxin
KFO61_RS16030 (KFO61_16025) 3273306..3273644 - 339 WP_002911404.1 YebY family protein -
KFO61_RS16035 (KFO61_16030) 3273661..3274530 - 870 WP_004203385.1 copper homeostasis membrane protein CopD -
KFO61_RS16040 (KFO61_16035) 3274534..3274908 - 375 WP_004203386.1 CopC domain-containing protein YobA -
KFO61_RS16045 (KFO61_16040) 3275021..3275251 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KFO61_RS16050 (KFO61_16045) 3275330..3275989 + 660 WP_004203387.1 exodeoxyribonuclease X -
KFO61_RS16055 (KFO61_16050) 3275993..3278053 - 2061 WP_004203388.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T200293 NZ_CP073791:c3273148-3273046 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT200293 NZ_CP073791:3273042-3273189 [Klebsiella pneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References