Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1894009..1894154 Replicon chromosome
Accession NZ_CP073783
Organism Klebsiella pneumoniae isolate KP_NORM_BLD_2014_96855

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1894045..1894147 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1894009..1894154 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFO63_RS09065 (KFO63_09055) 1889139..1891199 + 2061 WP_069339950.1 oligopeptidase B -
KFO63_RS09070 (KFO63_09060) 1891203..1891862 - 660 WP_002911407.1 exodeoxyribonuclease X -
KFO63_RS09075 (KFO63_09065) 1891941..1892171 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KFO63_RS09080 (KFO63_09070) 1892284..1892658 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KFO63_RS09085 (KFO63_09075) 1892662..1893531 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
KFO63_RS09090 (KFO63_09080) 1893548..1893886 + 339 WP_002911404.1 YebY family protein -
- 1894009..1894154 - 146 - - Antitoxin
- 1894045..1894147 + 103 - - Toxin
KFO63_RS09095 (KFO63_09085) 1894523..1894666 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
KFO63_RS09100 (KFO63_09090) 1894771..1895739 - 969 WP_004151446.1 VirK/YbjX family protein -
KFO63_RS09105 (KFO63_09095) 1895896..1896549 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
KFO63_RS09110 (KFO63_09100) 1896546..1896737 - 192 WP_002911395.1 YebW family protein -
KFO63_RS09115 (KFO63_09105) 1896835..1897074 - 240 WP_002911393.1 YebV family protein -
KFO63_RS09120 (KFO63_09110) 1897190..1898623 - 1434 WP_069339948.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T200250 NZ_CP073783:1894045-1894147 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT200250 NZ_CP073783:c1894154-1894009 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References