Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2063844..2064115 Replicon chromosome
Accession NZ_CP073719
Organism Escherichia coli strain CX12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2063974..2064077 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2063844..2064115 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6O05_RS10140 2060399..2061061 - 663 WP_000944256.1 exodeoxyribonuclease X -
J6O05_RS10145 2061085..2061741 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
J6O05_RS10150 2061843..2062073 - 231 WP_000916763.1 DNA polymerase III subunit theta -
J6O05_RS10155 2062212..2062586 + 375 WP_000168738.1 CopC domain-containing protein YobA -
J6O05_RS10160 2062590..2063462 + 873 WP_057108027.1 copper homeostasis membrane protein CopD -
J6O05_RS10165 2063475..2063816 + 342 WP_000976472.1 YebY family protein -
- 2063844..2064115 - 272 - - Antitoxin
- 2063974..2064077 + 104 - - Toxin
J6O05_RS10170 2064212..2064868 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
J6O05_RS10175 2064869..2065060 - 192 WP_001313035.1 YebW family protein -
J6O05_RS10180 2065165..2065401 - 237 WP_001295499.1 YebV family protein -
J6O05_RS10185 2065519..2066958 - 1440 WP_001383086.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T200112 NZ_CP073719:2063974-2064077 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT200112 NZ_CP073719:c2064115-2063844 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References