Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1673447..1673592 Replicon chromosome
Accession NZ_CP073377
Organism Klebsiella sp. P1927

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1673483..1673585 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1673447..1673592 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KB892_RS08275 (KB892_08275) 1668577..1670637 + 2061 WP_004151449.1 oligopeptidase B -
KB892_RS08280 (KB892_08280) 1670641..1671300 - 660 WP_002911407.1 exodeoxyribonuclease X -
KB892_RS08285 (KB892_08285) 1671379..1671609 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KB892_RS08290 (KB892_08290) 1671722..1672096 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KB892_RS08295 (KB892_08295) 1672100..1672969 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
KB892_RS08300 (KB892_08300) 1672986..1673324 + 339 WP_002911404.1 YebY family protein -
- 1673447..1673592 - 146 - - Antitoxin
- 1673483..1673585 + 103 - - Toxin
KB892_RS08305 (KB892_08305) 1673960..1674103 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KB892_RS08310 (KB892_08310) 1674208..1675176 - 969 WP_004151446.1 VirK/YbjX family protein -
KB892_RS08315 (KB892_08315) 1675333..1675986 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KB892_RS08320 (KB892_08320) 1675983..1676174 - 192 WP_002911395.1 YebW family protein -
KB892_RS08325 (KB892_08325) 1676272..1676511 - 240 WP_002911393.1 YebV family protein -
KB892_RS08330 (KB892_08330) 1676627..1678060 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T199812 NZ_CP073377:1673483-1673585 [Klebsiella sp. P1927]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT199812 NZ_CP073377:c1673592-1673447 [Klebsiella sp. P1927]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References