Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 30777..31420 Replicon plasmid plas1
Accession NZ_CP072992
Organism Loktanella salsilacus strain 1A07893

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KBK07_RS16020 Protein ID WP_254252831.1
Coordinates 31019..31420 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KBK07_RS16015 Protein ID WP_254252830.1
Coordinates 30777..31019 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBK07_RS16000 (KBK07_16025) 26777..28717 - 1941 WP_254252828.1 glycosyltransferase family 2 protein -
KBK07_RS16005 (KBK07_16030) 28844..29950 + 1107 WP_254252829.1 glycosyltransferase family 61 protein -
KBK07_RS16010 (KBK07_16035) 30121..30556 + 436 Protein_22 DDE-type integrase/transposase/recombinase -
KBK07_RS16015 (KBK07_16040) 30777..31019 + 243 WP_254252830.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KBK07_RS16020 (KBK07_16045) 31019..31420 + 402 WP_254252831.1 type II toxin-antitoxin system VapC family toxin Toxin
KBK07_RS16025 (KBK07_16050) 31450..32547 - 1098 WP_254252832.1 tyrosine-type recombinase/integrase -
KBK07_RS16030 (KBK07_16055) 32704..33606 + 903 WP_254252833.1 DUF1403 family protein -
KBK07_RS16035 (KBK07_16060) 33678..34199 + 522 WP_254252855.1 SMC-Scp complex subunit ScpB -
KBK07_RS16040 (KBK07_16065) 34309..35019 + 711 WP_254252834.1 IS6 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - ugd 1..138781 138781


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-117)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-49)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14800.02 Da        Isoelectric Point: 5.6661

>T199432 WP_254252831.1 NZ_CP072992:31019-31420 [Loktanella salsilacus]
MYILDTNVISAVRRPDRAPKVAAWLRGKAERELFLSVITLGEIERGIRQQETHDPMFAIDLRMWLDRTVLLFSDRLLAFE
AEDARIWGRLSAEIGHNGADLMIAASALRHGAIVVTGNISDFAPTGAALENPF

Download         Length: 402 bp

>T199432 NZ_CP097340:311834-312103 [Mannheimia haemolytica]
ATGCGAGAGATTGAGTATAGTAATGCTTTTAAACGTGACTATAAAAAATGTGCGGTTGAGTCTTTATCCTCTTCATTAAT
TGAGGCGTTGTATTTTCTGATTAATGACAAGCCATTACCTGAGAAATACTGCGATCACGCTTTAACCGGCGAATGGAAAG
GCTTTAGGGATTGCCATATCCAACCTGATTTGGTTCTTATCTATCGAAAAGTGGAAGATGATAAGCTAGAGCTGCTGCGA
ATTGGCAGCCACTCTCATTTATTTGGCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8654.92 Da        Isoelectric Point: 9.9248

>AT199432 WP_254252830.1 NZ_CP072992:30777-31019 [Loktanella salsilacus]
MWTVQDAKNKFSAVVDAALAGTPQEVTRRGKPAVVVLSSDEYHRLLKGAVKARESFAEHLMAFPGGDITRASAAPRDVIF

Download         Length: 243 bp

>AT199432 NZ_CP097340:311581-311847 [Mannheimia haemolytica]
ATGGCAAATAGTGCATTAGTAAGCGTAAGAATCAGCCCTGAAATTAAAGAGCAAGCAAGTGAGGTGTTAGCCGGTATCGG
CTTGACTGTCTCTGATGTGATGCGAATGACATTAGCGAAAATCGCAACAGAAAAACGTTTTCAGTTTGATTATCAGCCTA
ATTTTGAGACAGCAGAAGTATTAAGGGCTGTTAAGAATGGCGAGGAAAAGCTACATTCAGCAAATAGTATTGCGGATTTA
ATGGAGCAACTCAATGCGAGAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References