Detailed information of TA system TA197968

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2521863..2522188
• Replicon: chromosome
• Accession: NZ_CP072525
• Organism: Bacillus subtilis strain YB-04

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: J7W01_RS12890
• Protein ID: WP_128751232.1
• Coordinates: 2521863..2522042 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2521966..2522188 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J7W01_RS12880 (2521089)	2521089..2521226	-	138	WP_021480099.1	hypothetical protein	-
J7W01_RS12885 (2521268)	2521268..2521717	-	450	WP_032722171.1	phage portal protein	-
J7W01_RS12890 (2521863)	2521863..2522042	+	180	WP_128751232.1	type I toxin-antitoxin system toxin TxpA	Toxin
- (2521966)	2521966..2522188	-	223	NuclAT_0	-	Antitoxin
- (2521966)	2521966..2522188	-	223	NuclAT_0	-	Antitoxin
- (2521966)	2521966..2522188	-	223	NuclAT_0	-	Antitoxin
- (2521966)	2521966..2522188	-	223	NuclAT_0	-	Antitoxin
J7W01_RS12895 (2522422)	2522422..2522511	+	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
J7W01_RS12900 (2522765)	2522765..2523208	-	444	WP_003229930.1	phage tail tube protein	-
J7W01_RS12905 (2523211)	2523211..2524611	-	1401	WP_003229929.1	phage tail sheath family protein	-
J7W01_RS12910 (2524612)	2524612..2524803	-	192	WP_010886574.1	hypothetical protein	-
J7W01_RS12915 (2524800)	2524800..2525237	-	438	WP_003229927.1	hypothetical protein	-
J7W01_RS12920 (2525250)	2525250..2525753	-	504	WP_003246050.1	HK97 gp10 family phage protein	-
J7W01_RS12925 (2525750)	2525750..2526112	-	363	WP_003229925.1	YqbH/XkdH family protein	-
J7W01_RS12930 (2526109)	2526109..2526504	-	396	WP_004398566.1	DUF3199 family protein	-
J7W01_RS12935 (2526508)	2526508..2526819	-	312	WP_003229923.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2491372..2546739	55367

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-122)

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6755.19 Da
• Isoelectric Point: 8.0288

>T197968 WP_128751232.1 NZ_CP072525:2521863-2522042 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLYMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T197968 NZ_CP096839:71515-71916 [Mycobacterium tuberculosis variant bovis]
GTGGATGAATGTGTAGTCGACGCGGCGGCCGTGGTTGACGCTCTCGCCGGCAAGGGCGCCAGCGCGATCGTTCTGCGCGG
TTTGCTCAAGGAGTCGATTTCTAACGCGCCGCATTTGCTGGACGCAGAGGTCGGACATGCACTCCGCCGCGCCGTGCTCA
GCGACGAAATCTCCGAAGAGCAGGCTCGCGCCGCGTTGGATGCCTTGCCTTATCTCATCGACAATCGTTACCCGCACAGC
CCACGACTGATCGAATACACATGGCAGCTAAGGCACAACGTCACGTTCTACGACGCCCTTTACGTCGCACTGGCCACCGC
ACTGGATGTCCCGCTGCTCACGGGCGACTCGCGGCTTGCGGCCGCGCCGGGCCTTCCGTGCGAAATCAAACTCGTTCGGT
GA

Antitoxin

Nucleotide

• Length: 223 bp

>AT197968 NZ_CP072525:c2522188-2521966 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACTTGTTAATGTGTGTTA
CTTTCATGAGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAG
GAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Antitoxin