Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3625386..3625939 Replicon chromosome
Accession NZ_CP071409
Organism [Pantoea] beijingensis strain JZB2120001

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag J1C60_RS16445 Protein ID WP_128176051.1
Coordinates 3625386..3625700 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag J1C60_RS16450 Protein ID WP_128176049.1
Coordinates 3625703..3625939 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1C60_RS16420 3621014..3621412 + 399 WP_128176061.1 cag pathogenicity island Cag12 family protein -
J1C60_RS16425 3621457..3621759 + 303 WP_128176059.1 TrbM/KikA/MpfK family conjugal transfer protein -
J1C60_RS16430 3621809..3622114 + 306 WP_128176057.1 dpoa decarboxylase -
J1C60_RS16435 3622892..3624628 + 1737 WP_128176055.1 type IV secretory system conjugative DNA transfer family protein -
J1C60_RS16440 3624637..3625389 + 753 WP_128176053.1 MobC family replication-relaxation protein -
J1C60_RS16445 3625386..3625700 - 315 WP_128176051.1 CcdB family protein Toxin
J1C60_RS16450 3625703..3625939 - 237 WP_128176049.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
J1C60_RS16455 3626252..3627205 - 954 WP_128176047.1 zincin-like metallopeptidase domain-containing protein -
J1C60_RS16460 3627697..3628575 + 879 WP_128176045.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3594631..3637678 43047


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11531.41 Da        Isoelectric Point: 7.9888

>T196333 WP_128176051.1 NZ_CP071409:c3625700-3625386 [[Pantoea] beijingensis]
MQFTVYTNTGKSAVYPLLLDITSDIIGQLNRRIVIPLLPVDRYPAGRRPDRLVPVVRLTDGQEYAVMTHELASVPVRGLG
AVFCDASQYRTQVKAAIDFLIDGI

Download         Length: 315 bp

>T196333 NZ_CP095088:1817699-1817950 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8986.99 Da        Isoelectric Point: 6.4792

>AT196333 WP_128176049.1 NZ_CP071409:c3625939-3625703 [[Pantoea] beijingensis]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLSAALDAELRHHEAKKWQEENREAIDALNRFHDEHGCFSDEYRTF

Download         Length: 237 bp

>AT196333 NZ_CP095088:1817947-1818201 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References