Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 830848..831502 Replicon chromosome
Accession NZ_CP071409
Organism [Pantoea] beijingensis strain JZB2120001

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag J1C60_RS03795 Protein ID WP_128178191.1
Coordinates 831095..831502 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag J1C60_RS03790 Protein ID WP_128178189.1
Coordinates 830848..831114 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1C60_RS03770 826019..827530 - 1512 WP_128178182.1 PTS transporter subunit EIIC -
J1C60_RS03775 827889..828620 - 732 WP_128178184.1 MurR/RpiR family transcriptional regulator -
J1C60_RS03780 828944..829597 + 654 WP_128178186.1 hemolysin III family protein -
J1C60_RS03785 829637..830617 - 981 WP_128178187.1 tRNA-modifying protein YgfZ -
J1C60_RS03790 830848..831114 + 267 WP_128178189.1 FAD assembly factor SdhE Antitoxin
J1C60_RS03795 831095..831502 + 408 WP_128178191.1 protein YgfX Toxin
J1C60_RS03800 831551..832069 - 519 WP_128178193.1 flavodoxin FldB -
J1C60_RS03805 832266..833159 + 894 WP_128178195.1 site-specific tyrosine recombinase XerD -
J1C60_RS03810 833273..833980 + 708 WP_128178197.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
J1C60_RS03815 833987..835717 + 1731 WP_128178199.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-129)

Antitoxin

Flavinator of succinate dehydrogenase

(8-77)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 16093.21 Da        Isoelectric Point: 11.9497

>T196322 WP_128178191.1 NZ_CP071409:831095-831502 [[Pantoea] beijingensis]
VARWQSNLRVSRCAKRVSLALHGGAILFLVLAPWPPAYIPVWVLLFLMVLECCFSLRRIERRQGEISLLAPRLLYWRQQE
WLIVRSPWISPQGILLSLRSRKGQRECLWLMRDSMSQAAWHLLRQGLLTRWYRER

Download         Length: 408 bp

>T196322 NZ_CP095087:5776-6051 [Escherichia coli]
ATGGAACTGAAGTGGACCAGTAAGGCGCTTTCTAATTTGGCGCGGTTATATGATTTTCTGGTGCTGGCCAGTAAACCTGC
TGCCGCCAGAATGGTACAGTCCCTGACACAGGCACCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTGCTGGCGAGTACGAAATCCGTTACGAACTTAATGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.06 Da        Isoelectric Point: 4.8310

>AT196322 WP_128178189.1 NZ_CP071409:830848-831114 [[Pantoea] beijingensis]
MDINNRSRIHWACRRGMRELDISIMPFFEYEYDSLSDDDKQVFIRLLESDDPDLFNWMMNHGEPADPELKRMVQLIQIRN
KQRGPVAI

Download         Length: 267 bp

>AT196322 NZ_CP095087:5492-5776 [Escherichia coli]
ATACAAATGAAAAACAATACCGCACAGGCAACAAAAGTAATTACCGCGCATGTGCCATTACCTATGGCTGATAAAGTCGA
CCAGATGGCCGCCAGACTGGAACGCTCCCGGGGCTGGGTTATCAAACAGGCACTTTCTGCATGGCTTGCCCAGGAGGAGG
AGCGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGATTATCGACCATCAGGCTGTACAGGCCTGG
GCGGACAGCCTCAGTACTGACAATCCGTTACCGGTGCCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References