Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 367138..367283 Replicon chromosome
Accession NZ_CP070568
Organism Klebsiella pneumoniae strain KP51248

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 367174..367276 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 367138..367283 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JW300_RS02775 362268..364328 + 2061 WP_004151449.1 oligopeptidase B -
JW300_RS02780 364332..364991 - 660 WP_002911407.1 exodeoxyribonuclease X -
JW300_RS02785 365070..365300 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JW300_RS02790 365413..365787 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JW300_RS02795 365791..366660 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
JW300_RS02800 366677..367015 + 339 WP_002911404.1 YebY family protein -
- 367138..367283 - 146 - - Antitoxin
- 367174..367276 + 103 - - Toxin
JW300_RS02805 367651..367794 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JW300_RS02810 367899..368867 - 969 WP_004151446.1 VirK/YbjX family protein -
JW300_RS02815 369024..369677 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
JW300_RS02820 369674..369865 - 192 WP_002911395.1 YebW family protein -
JW300_RS02825 369963..370202 - 240 WP_002911393.1 YebV family protein -
JW300_RS02830 370318..371751 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T194354 NZ_CP070568:367174-367276 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT194354 NZ_CP070568:c367283-367138 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References