Detailed information of TA system TA194207

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3771786..3772236
• Replicon: chromosome
• Accession: NZ_CP070503
• Organism: Pseudomonas atacamensis strain SM1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JWU58_RS17050
• Protein ID: WP_082228561.1
• Coordinates: 3771967..3772236 (+)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A341FF08
• Locus tag: JWU58_RS17045
• Protein ID: WP_038862015.1
• Coordinates: 3771786..3771977 (+)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JWU58_RS17020	3767371..3768060	+	690	WP_206420599.1	N-acetyltransferase	-
JWU58_RS17025	3768064..3769254	+	1191	WP_206420600.1	GNAT family N-acetyltransferase	-
JWU58_RS17030	3769251..3769943	+	693	WP_123443213.1	N-acetyltransferase	-
JWU58_RS17035	3770256..3770564	+	309	WP_016774087.1	putative addiction module antidote protein	-
JWU58_RS17040	3770680..3771477	-	798	WP_125915893.1	class I SAM-dependent methyltransferase	-
JWU58_RS17045	3771786..3771977	+	192	WP_038862015.1	hypothetical protein	Antitoxin
JWU58_RS17050	3771967..3772236	+	270	WP_082228561.1	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	Toxin
JWU58_RS17055	3772309..3773208	-	900	WP_024012435.1	LysR family transcriptional regulator	-
JWU58_RS17060	3773424..3774446	+	1023	WP_206420601.1	alpha/beta hydrolase fold domain-containing protein	-
JWU58_RS17065	3774555..3775982	+	1428	WP_206420602.1	mechanosensitive ion channel	-
JWU58_RS17070	3776026..3776649	-	624	WP_016774080.1	hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10263.67 Da
• Isoelectric Point: 7.3990

>T194207 WP_082228561.1 NZ_CP070503:3771967-3772236 [Pseudomonas atacamensis]
MQIEWRPEAKADLSNILRYIGERNFAAAVSLSKSIEESTTSLSVHPHLYRKGRSPGTREIVVHPNYVVIYEVTDRIEILS
VLHTRQEYP

Nucleotide

• Length: 270 bp

>T194207 NZ_CP093390:798178-798576 [Salmonella enterica]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACGTCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCAGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTCTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTACCGAACTGGCCCGCAAGGGAACACCTGTCGGGTCTTATGACCAGATGATTGCTGGCCATGCCCGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAGTTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7132.82 Da
• Isoelectric Point: 4.5698

>AT194207 WP_038862015.1 NZ_CP070503:3771786-3771977 [Pseudomonas atacamensis]
MDGKIFPDDSGFENDEQAASHDRWLRAKVQASRDDPHPSLPHEDVMADMHALIESMRKKADAD

Nucleotide

• Length: 192 bp

>AT194207 NZ_CP093390:797951-798178 [Salmonella enterica]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCGGTCAGATTGCCTAAATCAATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGTAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGTG
AAGATGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTCTGA

Structures

Antitoxin

• AlphaFold DB: A0A341FF08