Detailed information of TA system TA193771

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 1137605..1137851
• Replicon: chromosome
• Accession: NZ_CP070296
• Organism: Escherichia albertii strain Sample 165

Toxin (Protein)

• Gene name: hokX
• Uniprot ID: S1PD89
• Locus tag: JRC44_RS05485
• Protein ID: WP_000956458.1
• Coordinates: 1137699..1137851 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokX
Locus tag	-
Coordinates	1137605..1137657 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JRC44_RS05470	1133009..1134808	+	1800	WP_208629639.1	NADPH-dependent assimilatory sulfite reductase flavoprotein subunit	-
JRC44_RS05475	1134808..1136520	+	1713	WP_208629640.1	assimilatory sulfite reductase (NADPH) hemoprotein subunit	-
JRC44_RS05480	1136700..1137434	+	735	WP_025238482.1	phosphoadenosine phosphosulfate reductase	-
-	1137605..1137657	-	53	-	-	Antitoxin
JRC44_RS05485	1137699..1137851	+	153	WP_000956458.1	Hok/Gef family protein	Toxin
JRC44_RS05490	1137977..1139014	-	1038	WP_059225076.1	alkaline phosphatase isozyme conversion aminopeptidase	-
JRC44_RS05495	1139267..1140175	+	909	WP_000372392.1	sulfate adenylyltransferase subunit CysD	-
JRC44_RS05500	1140177..1141604	+	1428	WP_208629641.1	sulfate adenylyltransferase subunit CysN	-
JRC44_RS05505	1141604..1142209	+	606	WP_024164730.1	adenylyl-sulfate kinase	-
JRC44_RS05510	1142259..1142582	+	324	WP_001246114.1	DUF3561 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (5-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5558.77 Da
• Isoelectric Point: 7.6757

>T193771 WP_000956458.1 NZ_CP070296:1137699-1137851 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Nucleotide

• Length: 153 bp

>T193771 NZ_CP093215:c1000980-1000684 [Mycoplasma mycoides subsp. capri]
ATGACTAAATATAAAATTGTTTGAACAACAAAATTTAAAAAGGATTTAAAGCTAGCTAAAAAACAGAATAAAGATTTAAA
TAAACTAGACTATGTTATTAATATATTAACTCAAGGCAAAGAGTTAGACGCAAAGTATCGTGACCATTCACTTACTGGCA
TTTATAAAGGATATAGAGAATGCCATATTGACCCCGACTGACTTTTAATTTATAAAAAAGATGATGATAAAATTGTTATA
ACAATGTTAAGACTAGGTTCACATTCTAATTTATTTGAAAAACAAAGAAACTACTAG

Antitoxin

Nucleotide

• Length: 53 bp

>AT193771 NZ_CP070296:c1137657-1137605 [Escherichia albertii]
TTAGGTTCGAACGTAGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Structures

Toxin

• AlphaFold DB: A0A4P7TJ83

Antitoxin