Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4297099..4297370 Replicon chromosome
Accession NZ_CP070077
Organism Escherichia coli strain FDAARGOS_1371

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4297229..4297332 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4297099..4297370 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L01_RS20205 4293654..4294316 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6L01_RS20210 4294340..4294996 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
I6L01_RS20215 4295098..4295328 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6L01_RS20220 4295467..4295841 + 375 WP_000204705.1 CopC domain-containing protein YobA -
I6L01_RS20225 4295845..4296717 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
I6L01_RS20230 4296730..4297071 + 342 WP_001520705.1 YebY family protein -
- 4297099..4297370 - 272 - - Antitoxin
- 4297229..4297332 + 104 - - Toxin
I6L01_RS20235 4297467..4298123 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
I6L01_RS20240 4298124..4298315 - 192 WP_001296140.1 YebW family protein -
I6L01_RS20245 4298420..4298656 - 237 WP_001295499.1 YebV family protein -
I6L01_RS20250 4298774..4300213 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T192994 NZ_CP070077:4297229-4297332 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT192994 NZ_CP070077:c4297370-4297099 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References