Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 994262..994530 Replicon chromosome
Accession NZ_CP069978
Organism Escherichia coli strain FDAARGOS_1299

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 994390..994492 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 994262..994530 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K29_RS04600 990816..991478 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6K29_RS04605 991501..992157 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
I6K29_RS04610 992259..992489 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6K29_RS04615 992628..993002 + 375 WP_000168747.1 CopC domain-containing protein YobA -
I6K29_RS04620 993006..993878 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
I6K29_RS04625 993891..994232 + 342 WP_000984819.1 YebY family protein -
- 994262..994530 - 269 - - Antitoxin
- 994390..994492 + 103 - - Toxin
I6K29_RS04630 994627..995283 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
I6K29_RS04635 995284..995475 - 192 WP_001296140.1 YebW family protein -
I6K29_RS04640 995580..995816 - 237 WP_001295499.1 YebV family protein -
I6K29_RS04645 995934..997373 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192433 NZ_CP069978:994390-994492 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT192433 NZ_CP069978:c994530-994262 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References