Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4695913..4696058 Replicon chromosome
Accession NZ_CP069939
Organism Klebsiella pneumoniae strain FDAARGOS_1318

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4695949..4696051 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4695913..4696058 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K48_RS22765 4691043..4693103 + 2061 WP_004151449.1 oligopeptidase B -
I6K48_RS22770 4693107..4693766 - 660 WP_002911407.1 exodeoxyribonuclease X -
I6K48_RS22775 4693845..4694075 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K48_RS22780 4694188..4694562 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K48_RS22785 4694566..4695435 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
I6K48_RS22790 4695452..4695790 + 339 WP_004189269.1 YebY family protein -
- 4695913..4696058 - 146 - - Antitoxin
- 4695949..4696051 + 103 - - Toxin
I6K48_RS22795 4696425..4696568 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6K48_RS22800 4696673..4697641 - 969 WP_004151446.1 VirK/YbjX family protein -
I6K48_RS22805 4697798..4698451 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
I6K48_RS22810 4698448..4698639 - 192 WP_002911395.1 YebW family protein -
I6K48_RS22815 4698737..4698976 - 240 WP_002911393.1 YebV family protein -
I6K48_RS22820 4699092..4700525 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192180 NZ_CP069939:4695949-4696051 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192180 NZ_CP069939:c4696058-4695913 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References