Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4530733..4530878 Replicon chromosome
Accession NZ_CP069861
Organism Klebsiella pneumoniae strain FDAARGOS_1311

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4530740..4530842 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4530733..4530878 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K41_RS22090 4526264..4527697 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K41_RS22095 4527813..4528052 + 240 WP_002911393.1 YebV family protein -
I6K41_RS22100 4528150..4528341 + 192 WP_002911395.1 YebW family protein -
I6K41_RS22105 4528338..4528991 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
I6K41_RS22110 4529148..4530116 + 969 WP_004151446.1 VirK/YbjX family protein -
I6K41_RS22115 4530221..4530364 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4530733..4530878 + 146 - - Antitoxin
- 4530740..4530842 - 103 - - Toxin
I6K41_RS22120 4531001..4531339 - 339 WP_009307539.1 YebY family protein -
I6K41_RS22125 4531356..4532225 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
I6K41_RS22130 4532229..4532603 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K41_RS22135 4532716..4532946 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K41_RS22140 4533025..4533684 + 660 WP_002911407.1 exodeoxyribonuclease X -
I6K41_RS22145 4533688..4535748 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T191934 NZ_CP069861:c4530842-4530740 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT191934 NZ_CP069861:4530733-4530878 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References