Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 955750..956407 Replicon chromosome
Accession NZ_CP069815
Organism Raoultella planticola strain HH15

Toxin (Protein)


Gene name cptA Uniprot ID A0A2X2EG10
Locus tag G9395_RS04725 Protein ID WP_032690815.1
Coordinates 955997..956407 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A514ELX1
Locus tag G9395_RS04720 Protein ID WP_004867358.1
Coordinates 955750..956016 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G9395_RS04695 950897..952330 - 1434 WP_032690812.1 6-phospho-beta-glucosidase -
G9395_RS04700 952450..953178 - 729 WP_032690813.1 MurR/RpiR family transcriptional regulator -
G9395_RS04705 953228..953539 + 312 WP_004867365.1 N(4)-acetylcytidine aminohydrolase -
G9395_RS04710 953701..954360 + 660 WP_004867362.1 hemolysin III family protein -
G9395_RS04715 954470..955453 - 984 WP_032690814.1 tRNA-modifying protein YgfZ -
G9395_RS04720 955750..956016 + 267 WP_004867358.1 FAD assembly factor SdhE Antitoxin
G9395_RS04725 955997..956407 + 411 WP_032690815.1 protein YgfX Toxin
G9395_RS04730 956413..956934 - 522 WP_032690816.1 flavodoxin FldB -
G9395_RS04735 957113..958009 + 897 WP_032690817.1 site-specific tyrosine recombinase XerD -
G9395_RS04740 958032..958745 + 714 WP_032690818.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
G9395_RS04745 958751..960484 + 1734 WP_032696678.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16198.10 Da        Isoelectric Point: 11.3349

>T191838 WP_032690815.1 NZ_CP069815:955997-956407 [Raoultella planticola]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWVAADSMDAKEWRDLRRLVLQKPAQD

Download         Length: 411 bp

>T191838 NZ_CP091946:40604-40945 [Leptospira noguchii]
TTGGTAAAGAATAGAAACTATACTCCTGAAAAAGGAGATATTGTGTGGCTGAACTTTACTCCTCAAGCAGGTCATGAACA
GAAAGGTCGTAGACCTGCACTTGTTTTATCGCCTAAGGAATATAATTCAAAAACAGGGTTAGCAATATTTTGTCCAATTA
CCAGTAAAATTAAAGGTTATCCATTCGAAGTGTTGATTAAATCAAAAAAAATCGATGGTGTAATTCTTTCTGATCAAGTA
AAAAACTTAGATTGGACTATCCGTGAAGCAGAATTTATTGAATCAATAAATAAAGTTTCTTTAAAAGAAGTTTTAGATAA
TATTAAACTATTAATATTCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10553.05 Da        Isoelectric Point: 4.8432

>AT191838 WP_004867358.1 NZ_CP069815:955750-956016 [Raoultella planticola]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT191838 NZ_CP091946:40374-40610 [Leptospira noguchii]
ATGGAATCAATTATTCAAAAATGGGGTAATAGCTTAGGAATTAGAATTCCAAAAGCAATGGCAACGGAATTAGAGTTAAA
TGATGGAAGCCATGTTGAATTACAATATGAAGGAGATAAGATTGTAATATATCCAATGAAAAAAGCTTCATTGGAAGATA
AACTTTCTAAAATTACGAAACAAAATCTTCACTCTGAAATATCTACTGGTAATTCTATAGGCAATGAAGCTTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2X2EG10

Antitoxin

Source ID Structure
AlphaFold DB A0A514ELX1

References