Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 2413181..2413830 | Replicon | chromosome |
Accession | NZ_CP069798 | ||
Organism | Paralysiella testudinis strain 26B |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | JQU52_RS12320 | Protein ID | WP_230338771.1 |
Coordinates | 2413181..2413579 (-) | Length | 133 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | JQU52_RS12325 | Protein ID | WP_230338772.1 |
Coordinates | 2413591..2413830 (-) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JQU52_RS12305 (JQU52_12310) | 2408437..2410842 | + | 2406 | WP_230338769.1 | SNF2-related protein | - |
JQU52_RS12310 (JQU52_12315) | 2411169..2412275 | + | 1107 | WP_230338770.1 | DUF6094 domain-containing protein | - |
JQU52_RS12315 (JQU52_12320) | 2412416..2413074 | - | 659 | Protein_2405 | transposase | - |
JQU52_RS12320 (JQU52_12325) | 2413181..2413579 | - | 399 | WP_230338771.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
JQU52_RS12325 (JQU52_12330) | 2413591..2413830 | - | 240 | WP_230338772.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
JQU52_RS12330 (JQU52_12335) | 2414124..2414762 | + | 639 | WP_230338773.1 | hypothetical protein | - |
JQU52_RS12335 (JQU52_12340) | 2414912..2415646 | + | 735 | WP_230338774.1 | hypothetical protein | - |
JQU52_RS12340 (JQU52_12345) | 2415746..2416051 | - | 306 | WP_230338775.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
JQU52_RS12345 (JQU52_12350) | 2416053..2416361 | - | 309 | WP_230338776.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
JQU52_RS12350 (JQU52_12355) | 2416491..2417797 | - | 1307 | Protein_2412 | IS5 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 2412416..2412571 | 155 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 14196.38 Da Isoelectric Point: 6.1191
>T191806 WP_230338771.1 NZ_CP069798:c2413579-2413181 [Paralysiella testudinis]
MLDTNMVSHVLKQQAAVMDRLQSVPMASLCISAITHAEISYGLAKKPDAHTLHRAVAEFLLRVAVLPFDEQAAQDYGLLK
AGIEGMGKSLAPLDMLIAAHAHSIGATLISNDQAFHKITGLAVQDWTQPDPD
MLDTNMVSHVLKQQAAVMDRLQSVPMASLCISAITHAEISYGLAKKPDAHTLHRAVAEFLLRVAVLPFDEQAAQDYGLLK
AGIEGMGKSLAPLDMLIAAHAHSIGATLISNDQAFHKITGLAVQDWTQPDPD
Download Length: 399 bp
>T191806 NZ_CP091913:5247287-5247511 [Nostoc sp. UHCC 0870]
ATGAGCAGTATTCCTGTTTTGAAACCTCAAGAGGTTGTTCGCATACTAGAAAATCTCGGTTTTGTAGAAGTTCGTCAAAG
AGGTTCACATAAGCAGTTTCGCCATGAAGACGGTCGAGCAACAACTGTTCCATTTCACAAAGGTCGTGATATTTCCCCCA
GACTGCTCAAACAGATTGCGAGTGACGTTGAATTGACAGTTGAAGAGTTTTTGGAATCCAGGTAA
ATGAGCAGTATTCCTGTTTTGAAACCTCAAGAGGTTGTTCGCATACTAGAAAATCTCGGTTTTGTAGAAGTTCGTCAAAG
AGGTTCACATAAGCAGTTTCGCCATGAAGACGGTCGAGCAACAACTGTTCCATTTCACAAAGGTCGTGATATTTCCCCCA
GACTGCTCAAACAGATTGCGAGTGACGTTGAATTGACAGTTGAAGAGTTTTTGGAATCCAGGTAA
Antitoxin
Download Length: 80 a.a. Molecular weight: 9079.10 Da Isoelectric Point: 5.0477
>AT191806 WP_230338772.1 NZ_CP069798:c2413830-2413591 [Paralysiella testudinis]
MQIAKLFNNGRSQAVRLPAAFRFDGDSVYIRRDKNGDVILSKRPSDWQGFIVAANQLDGETIERDLTAHNRDVFEDWPE
MQIAKLFNNGRSQAVRLPAAFRFDGDSVYIRRDKNGDVILSKRPSDWQGFIVAANQLDGETIERDLTAHNRDVFEDWPE
Download Length: 240 bp
>AT191806 NZ_CP091913:5247074-5247283 [Nostoc sp. UHCC 0870]
ATGAAAACCTTTACTGCGGTTGTTGAGAAAGACATGGACACTGGTTTATATGTGGGCTACGTTCCTGGGTTTCCTGGCGC
GCATTCTCAAGCTGAAACTTTAGACGAGTTACAGATGAATCTGCGTGAAGTAATCGAGATGTTACTAGAGGATAAAAATC
CAACTTTCACAACTGAATTTGTTGGTACTCAGCAAATTGTCATTTCTTAG
ATGAAAACCTTTACTGCGGTTGTTGAGAAAGACATGGACACTGGTTTATATGTGGGCTACGTTCCTGGGTTTCCTGGCGC
GCATTCTCAAGCTGAAACTTTAGACGAGTTACAGATGAATCTGCGTGAAGTAATCGAGATGTTACTAGAGGATAAAAATC
CAACTTTCACAACTGAATTTGTTGGTACTCAGCAAATTGTCATTTCTTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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