Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1095407..1095921 Replicon chromosome
Accession NZ_CP069798
Organism Paralysiella testudinis strain 26B

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag JQU52_RS05590 Protein ID WP_230340151.1
Coordinates 1095407..1095670 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag JQU52_RS05595 Protein ID WP_230340152.1
Coordinates 1095667..1095921 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JQU52_RS05555 (JQU52_05585) 1090512..1090940 + 429 WP_230340144.1 single-stranded DNA-binding protein -
JQU52_RS05560 (JQU52_05590) 1091055..1091282 + 228 WP_230340145.1 type II toxin-antitoxin system VapB family antitoxin -
JQU52_RS05565 (JQU52_05595) 1091282..1091689 + 408 WP_230340146.1 tRNA(fMet)-specific endonuclease VapC -
JQU52_RS05570 (JQU52_05600) 1091916..1092191 + 276 WP_230340147.1 DUF1778 domain-containing protein -
JQU52_RS05575 (JQU52_05605) 1092194..1092700 + 507 WP_230340148.1 GNAT family N-acetyltransferase -
JQU52_RS05580 (JQU52_05610) 1092761..1094761 + 2001 WP_230340149.1 type IV secretory system conjugative DNA transfer family protein -
JQU52_RS05585 (JQU52_05615) 1094856..1095377 + 522 WP_230340150.1 hypothetical protein -
JQU52_RS05590 (JQU52_05620) 1095407..1095670 - 264 WP_230340151.1 Txe/YoeB family addiction module toxin Toxin
JQU52_RS05595 (JQU52_05625) 1095667..1095921 - 255 WP_230340152.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
JQU52_RS05600 (JQU52_05630) 1096044..1096802 + 759 WP_230340153.1 hypothetical protein -
JQU52_RS05605 (JQU52_05635) 1096805..1097194 + 390 WP_230340154.1 hypothetical protein -
JQU52_RS05610 (JQU52_05640) 1097241..1097846 + 606 WP_230340155.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1062617..1127893 65276


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10722.34 Da        Isoelectric Point: 8.8723

>T191798 WP_230340151.1 NZ_CP069798:c1095670-1095407 [Paralysiella testudinis]
MMLAWADDAWDDYLYWQQTDKRMLKRINMLLKDIQRQPFSGLGDPEPLKHNWSDFWSRRIDKEHRLVYRVSNDMVMVAQC
RYHYGKL

Download         Length: 264 bp

>T191798 NZ_CP091907:147320-147430 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9296.47 Da        Isoelectric Point: 5.0210

>AT191798 WP_230340152.1 NZ_CP069798:c1095921-1095667 [Paralysiella testudinis]
MDTMSYSAFRAGLAGVLDKVNDNHKPVLVTRQNGKPAVVMSLEDFQSYEETAYLMASPPNAERLNRAVAQIRAGETQQHG
MLEE

Download         Length: 255 bp

>AT191798 NZ_CP091907:c147534-147470 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References