Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2552074..2552342 Replicon chromosome
Accession NZ_CP069559
Organism Escherichia coli strain FDAARGOS_1259

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2552202..2552304 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2552074..2552342 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6J89_RS12115 2548628..2549290 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6J89_RS12120 2549313..2549969 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
I6J89_RS12125 2550071..2550301 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6J89_RS12130 2550440..2550814 + 375 WP_000168747.1 CopC domain-containing protein YobA -
I6J89_RS12135 2550818..2551690 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
I6J89_RS12140 2551703..2552044 + 342 WP_000977376.1 YebY family protein -
- 2552074..2552342 - 269 - - Antitoxin
- 2552202..2552304 + 103 - - Toxin
I6J89_RS12145 2552439..2553095 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
I6J89_RS12150 2553096..2553287 - 192 WP_001296140.1 YebW family protein -
I6J89_RS12155 2553392..2553628 - 237 WP_001295499.1 DUF1480 family protein -
I6J89_RS12160 2553746..2555185 - 1440 WP_001467894.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T190904 NZ_CP069559:2552202-2552304 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT190904 NZ_CP069559:c2552342-2552074 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References