Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 2326790..2327012 Replicon chromosome
Accession NZ_CP069386
Organism Escherichia coli strain XH1815

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag JSW75_RS11265 Protein ID WP_000141634.1
Coordinates 2326790..2326897 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 2326946..2327012 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JSW75_RS11240 2322043..2322771 - 729 WP_011310329.1 cellulose biosynthesis protein BcsQ -
JSW75_RS11245 2322807..2322995 - 189 WP_001063318.1 cellulose biosynthesis protein BcsR -
JSW75_RS11250 2323268..2324839 + 1572 WP_001204931.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
JSW75_RS11255 2324836..2325027 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
JSW75_RS11260 2325024..2326703 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
JSW75_RS11265 2326790..2326897 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 2326946..2327012 + 67 - - Antitoxin
JSW75_RS11270 2327373..2328644 + 1272 WP_001295225.1 aromatic amino acid transport family protein -
JSW75_RS11275 2328674..2329678 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
JSW75_RS11280 2329675..2330658 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
JSW75_RS11285 2330669..2331571 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T190313 WP_000141634.1 NZ_CP069386:c2326897-2326790 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T190313 NZ_CP091240:2727444-2727641 [Enterococcus faecalis]
ATGTGTAGAGAAGTTATGGCGGTGGCTATCCAATCTGAAAGAGAGGTGATGCGTATGCACGTATTTCCGAAATTTAGAGA
AAGGAGAGGCCTTTTGTCAGCATATGAAACAATTCAGACAATTCTTGGGTTTGGTATGTTTACCATTGCTTTGATTGCGC
TGATTGTGAAATTGCTTAAAAATGACAAGAAAAAATAA

Antitoxin


Download         Length: 67 bp

>AT190313 NZ_CP069386:2326946-2327012 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References