Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ralRA/- |
Location | 121686..122057 | Replicon | chromosome |
Accession | NZ_CP068827 | ||
Organism | Escherichia coli strain RIVM_C030371 |
Toxin (Protein)
Gene name | ralR | Uniprot ID | F4VC37 |
Locus tag | JNN58_RS00600 | Protein ID | WP_001317028.1 |
Coordinates | 121863..122057 (-) | Length | 65 a.a. |
Antitoxin (RNA)
Gene name | ralA | ||
Locus tag | - | ||
Coordinates | 121686..121864 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JNN58_RS00575 | 117641..119014 | + | 1374 | WP_001551034.1 | ATP-dependent RNA helicase DbpA | - |
JNN58_RS00580 | 119143..120078 | - | 936 | WP_000662472.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
JNN58_RS00585 | 120130..121365 | - | 1236 | WP_001551035.1 | site-specific integrase | - |
JNN58_RS00590 | 121367..121582 | - | 216 | WP_000079604.1 | excisionase XisR | - |
JNN58_RS00595 | 121682..121870 | - | 189 | WP_001551036.1 | DUF1187 family protein | - |
- | 121686..121864 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 121686..121864 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 121686..121864 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 121686..121864 | + | 179 | NuclAT_0 | - | Antitoxin |
JNN58_RS00600 | 121863..122057 | - | 195 | WP_001317028.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
JNN58_RS00605 | 122114..122923 | - | 810 | WP_001551037.1 | recombination protein RecT | - |
JNN58_RS00610 | 122916..125567 | - | 2652 | WP_001551038.1 | exodeoxyribonuclease VIII | - |
JNN58_RS00615 | 125669..125944 | - | 276 | WP_001314664.1 | hypothetical protein | - |
JNN58_RS00620 | 126019..126189 | - | 171 | WP_001551041.1 | phage protein | - |
JNN58_RS00625 | 126189..126410 | - | 222 | WP_000560221.1 | killing protein KilR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 120130..167544 | 47414 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7018.89 Da Isoelectric Point: 8.9538
>T188667 WP_001317028.1 NZ_CP068827:c122057-121863 [Escherichia coli]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
Download Length: 195 bp
>T188667 NZ_CP090529:4781791-4782102 [Salmonella enterica]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAAGAATGA
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAAGAATGA
Antitoxin
Download Length: 179 bp
>AT188667 NZ_CP068827:121686-121864 [Escherichia coli]
GAGGACTGAAGTCTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGGCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTCTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGGCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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