Detailed information of TA system TA187162

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 1438632..1439034
• Replicon: chromosome
• Accession: NZ_CP068386
• Organism: Salmonella enterica subsp. enterica serovar Gallinarum/Pullorum strain R51

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: JI728_RS06810
• Protein ID: WP_001675090.1
• Coordinates: 1438632..1438766 (-)
• Length: 45 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	1438682..1439034 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JI728_RS06795	1434318..1437118	+	2801	Protein_1325	AAA family ATPase	-
JI728_RS06800	1437084..1437449	+	366	WP_000517964.1	hypothetical protein	-
JI728_RS06805	1438229..1438549	+	321	WP_223201872.1	Imm8 family immunity protein	-
JI728_RS06810	1438632..1438766	-	135	WP_001675090.1	hypothetical protein	Toxin
-	1438682..1439034	+	353	-	-	Antitoxin
JI728_RS06815	1439211..1439444	+	234	WP_124084119.1	hypothetical protein	-
JI728_RS06820	1439480..1439644	+	165	WP_001746938.1	hypothetical protein	-
JI728_RS06825	1440314..1440712	+	399	WP_000828171.1	hypothetical protein	-
JI728_RS06830	1441098..1441376	+	279	WP_077677834.1	hypothetical protein	-
JI728_RS06835	1441508..1441756	-	249	WP_001746936.1	SymE family type I addiction module toxin	-
JI728_RS06840	1441809..1442513	+	705	Protein_1334	integrase core domain-containing protein	-
JI728_RS06845	1443135..1443632	+	498	WP_001030293.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1413477..1450466	36989
	-	flank	IS/Tn	-	-	1442232..1442513	281

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4692.40 Da
• Isoelectric Point: 4.4551

>T187162 WP_001675090.1 NZ_CP068386:c1438766-1438632 [Salmonella enterica subsp. enterica serovar Gallinarum/Pullorum]
VTVKISDGCIVLMADGNEVQELREQLYQAKRVVKGGEGCAGLVD

Nucleotide

• Length: 135 bp

>T187162 NZ_CP089778:3837391-3837801 [Mycobacterium tuberculosis]
GTGATCTATATGGACACCTCGGCCCTGACTAAGCTGCTCATCTCCGAGCCCGAGACGACCGAACTGCGGACATGGCTGAC
CGCGCAAAGCGGCCAGGGCGAGGACGCGGCGACAAGCACCCTTGGCCGGGTCGAGTTGATGAGAGTCGTTGCCCGATACG
GACAACCAGGCCAAACTGAGCGTGCGCGTTACCTACTCGACGGGCTCGACATCCTCCCGCTCACCGAACCGGTGATCGGT
CTAGCTGAAACGATCGGACCGGCCACCCTACGTTCTCTCGACGCGATTCACCTCGCGGCCGCAGCCCAGATCAAGCGGGA
ACTGACAGCCTTCGTCACCTACGACCACCGATTGTTGAGCGGATGCCGTGAGGTCGGCTTCGTCACCGCCTCACCCGGCG
CAGTCCGGTGA

Antitoxin

Nucleotide

• Length: 353 bp

>AT187162 NZ_CP068386:1438682-1439034 [Salmonella enterica subsp. enterica serovar Gallinarum/Pullorum]
CCTGATAAAGCTGTTCGCGCAGCTCCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCTTCACC
GTCACGCCGCTCCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCCGGGGATTTGTGAGTAACAGGTGGTCATGC
AGGTTTCGCTGTTGATGTGGCGGACGCTGGCGCCGGAGGTATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCC
GGATGCTGGCTGATTGTGGAGCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCCCCCTCTCCCCGGCCA
GTGATGAGCAACCGGCTACCGGGGCCGTATTTT

Structures

Antitoxin