Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2123878..2124046 Replicon chromosome
Accession NZ_CP067391
Organism Klebsiella grimontii strain 5512.56

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2123936..2124039 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2123878..2124046 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JJJ11_RS12395 (JJJ11_12395) 2119005..2121065 + 2061 WP_209574004.1 oligopeptidase B -
JJJ11_RS12400 (JJJ11_12400) 2121072..2121731 - 660 WP_004134816.1 exodeoxyribonuclease X -
JJJ11_RS12405 (JJJ11_12405) 2121810..2122040 - 231 WP_004103351.1 DNA polymerase III subunit theta -
JJJ11_RS12410 (JJJ11_12410) 2122176..2122550 + 375 WP_004134817.1 CopC domain-containing protein YobA -
JJJ11_RS12415 (JJJ11_12415) 2122555..2123424 + 870 WP_209574006.1 copper homeostasis membrane protein CopD -
JJJ11_RS12420 (JJJ11_12420) 2123441..2123779 + 339 WP_004103344.1 YebY family protein -
- 2123878..2124046 - 169 - - Antitoxin
- 2123936..2124039 + 104 - - Toxin
JJJ11_RS12425 (JJJ11_12425) 2124164..2125123 - 960 WP_209574007.1 spore coat protein U domain-containing protein -
JJJ11_RS12430 (JJJ11_12430) 2125138..2127468 - 2331 WP_049089570.1 fimbria/pilus outer membrane usher protein -
JJJ11_RS12435 (JJJ11_12435) 2127471..2128235 - 765 WP_004134823.1 fimbria/pilus periplasmic chaperone -
JJJ11_RS12440 (JJJ11_12440) 2128254..2128772 - 519 WP_209574009.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T186224 NZ_CP067391:2123936-2124039 [Klebsiella grimontii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT186224 NZ_CP067391:c2124046-2123878 [Klebsiella grimontii]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References