Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1920014..1920159 Replicon chromosome
Accession NZ_CP067045
Organism Klebsiella pneumoniae strain B6753

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1920050..1920152 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1920014..1920159 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IL988_RS09365 1915144..1917204 + 2061 WP_049181698.1 oligopeptidase B -
IL988_RS09370 1917208..1917867 - 660 WP_002911407.1 exodeoxyribonuclease X -
IL988_RS09375 1917946..1918176 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IL988_RS09380 1918289..1918663 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IL988_RS09385 1918667..1919536 + 870 WP_049181704.1 copper homeostasis membrane protein CopD -
IL988_RS09390 1919553..1919891 + 339 WP_002911404.1 YebY family protein -
- 1920014..1920159 - 146 - - Antitoxin
- 1920050..1920152 + 103 - - Toxin
IL988_RS09395 1920528..1920671 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IL988_RS09400 1920776..1921744 - 969 WP_014907334.1 VirK/YbjX family protein -
IL988_RS09405 1921901..1922554 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
IL988_RS09410 1922551..1922742 - 192 WP_002911395.1 YebW family protein -
IL988_RS09415 1922840..1923079 - 240 WP_002911393.1 YebV family protein -
IL988_RS09420 1923195..1924628 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T185617 NZ_CP067045:1920050-1920152 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT185617 NZ_CP067045:c1920159-1920014 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References