Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2935725..2935928 Replicon chromosome
Accession NZ_CP065939
Organism Enterobacter hormaechei strain MSB1_8J

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2935732..2935835 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2935725..2935928 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JDC97_RS14375 2931114..2931794 + 681 WP_022651073.1 YqaJ viral recombinase family protein -
JDC97_RS14380 2931791..2932219 + 429 WP_022651072.1 hypothetical protein -
JDC97_RS14385 2932216..2932368 + 153 WP_022651071.1 DUF1317 family protein -
JDC97_RS14390 2932365..2932916 + 552 WP_022651070.1 phage N-6-adenine-methyltransferase -
JDC97_RS14395 2932913..2933131 + 219 WP_032621601.1 hypothetical protein -
JDC97_RS14400 2933450..2933668 + 219 WP_058656544.1 TraR/DksA family transcriptional regulator -
JDC97_RS14405 2933668..2933907 + 240 WP_058656543.1 DUF4222 domain-containing protein -
JDC97_RS14410 2933913..2934125 - 213 WP_045617122.1 hypothetical protein -
JDC97_RS14415 2934328..2934600 + 273 WP_023300430.1 hypothetical protein -
JDC97_RS14420 2934569..2935654 + 1086 WP_058691373.1 phage integrase Arm DNA-binding domain-containing protein -
- 2935725..2935928 + 204 - - Antitoxin
- 2935732..2935835 - 104 - - Toxin
JDC97_RS14425 2935977..2936315 - 339 WP_003859787.1 YebY family protein -
JDC97_RS14430 2936332..2937201 - 870 WP_022651438.1 copper homeostasis membrane protein CopD -
JDC97_RS14435 2937203..2937574 - 372 WP_022651439.1 CopC domain-containing protein YobA -
JDC97_RS14440 2937712..2937942 + 231 WP_003859784.1 DNA polymerase III subunit theta -
JDC97_RS14445 2938054..2938704 + 651 WP_003859783.1 carbon-nitrogen hydrolase family protein -
JDC97_RS14450 2938729..2939391 + 663 WP_015570288.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrA / gtrB 2881027..2956673 75646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T183632 NZ_CP065939:c2935835-2935732 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 204 bp

>AT183632 NZ_CP065939:2935725-2935928 [Enterobacter hormaechei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References