Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1876025..1876170 | Replicon | chromosome |
| Accession | NZ_CP065833 | ||
| Organism | Klebsiella pneumoniae strain KpC5 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1876061..1876163 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1876025..1876170 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I8N78_RS09145 | 1871155..1873215 | + | 2061 | WP_198068684.1 | oligopeptidase B | - |
| I8N78_RS09150 | 1873219..1873878 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| I8N78_RS09155 | 1873957..1874187 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| I8N78_RS09160 | 1874300..1874674 | + | 375 | WP_126438535.1 | CopC domain-containing protein YobA | - |
| I8N78_RS09165 | 1874678..1875547 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| I8N78_RS09170 | 1875564..1875902 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 1876025..1876170 | - | 146 | - | - | Antitoxin |
| - | 1876061..1876163 | + | 103 | - | - | Toxin |
| I8N78_RS09175 | 1876537..1876680 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| I8N78_RS09180 | 1876785..1877753 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| I8N78_RS09185 | 1877910..1878563 | + | 654 | WP_020802220.1 | protein-serine/threonine phosphatase | - |
| I8N78_RS09190 | 1878560..1878751 | - | 192 | WP_002911395.1 | YebW family protein | - |
| I8N78_RS09195 | 1878849..1879088 | - | 240 | WP_002911393.1 | YebV family protein | - |
| I8N78_RS09200 | 1879204..1880637 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T183460 NZ_CP065833:1876061-1876163 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT183460 NZ_CP065833:c1876170-1876025 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
