Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 2941..3166 | Replicon | chromosome |
Accession | NZ_CP065624 | ||
Organism | Escherichia coli strain FDAARGOS_941 |
Toxin (Protein)
Gene name | hokW | Uniprot ID | S1ELB5 |
Locus tag | I6G98_RS00785 | Protein ID | WP_000813254.1 |
Coordinates | 2941..3096 (-) | Length | 52 a.a. |
Antitoxin (RNA)
Gene name | sokW | ||
Locus tag | - | ||
Coordinates | 3108..3166 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6G98_RS00765 | 389..1072 | - | 684 | WP_032359563.1 | antiterminator | - |
I6G98_RS00770 | 1069..1434 | - | 366 | WP_000140020.1 | RusA family crossover junction endodeoxyribonuclease | - |
I6G98_RS00775 | 1435..2493 | - | 1059 | WP_197932854.1 | DUF968 domain-containing protein | - |
I6G98_RS00780 | 2495..2773 | - | 279 | WP_197932975.1 | hypothetical protein | - |
I6G98_RS00785 | 2941..3096 | - | 156 | WP_000813254.1 | type I toxin-antitoxin system toxin HokD | Toxin |
- | 3108..3166 | + | 59 | - | - | Antitoxin |
I6G98_RS00790 | 3748..4164 | - | 417 | WP_005069274.1 | hypothetical protein | - |
I6G98_RS00795 | 4261..4416 | - | 156 | Protein_6 | ead/Ea22-like family protein | - |
I6G98_RS00805 | 5678..5983 | - | 306 | Protein_8 | ead/Ea22-like family protein | - |
I6G98_RS00810 | 5970..6275 | - | 306 | WP_001266147.1 | DUF4406 domain-containing protein | - |
I6G98_RS00815 | 6272..6694 | - | 423 | WP_032359565.1 | DUF977 family protein | - |
I6G98_RS00820 | 6735..7805 | - | 1071 | WP_073840766.1 | phage replisome organizer | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 52 a.a. Molecular weight: 5736.89 Da Isoelectric Point: 6.1531
>T183053 WP_000813254.1 NZ_CP065624:c3096-2941 [Escherichia coli]
MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEPEE
MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEPEE
Download Length: 156 bp
>T183053 NZ_CP086627:1115325-1115732 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
Antitoxin
Download Length: 59 bp
>AT183053 NZ_CP065624:3108-3166 [Escherichia coli]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGTTCAGCATGGATTGAGCCTCA
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGTTCAGCATGGATTGAGCCTCA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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