Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 423869..424003 Replicon chromosome
Accession NZ_CP065613
Organism Escherichia coli strain FDAARGOS_944

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 423907..424003 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 423869..424000 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H01_RS02030 421026..422465 + 1440 WP_038339011.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6H01_RS02035 422583..422819 + 237 WP_001295499.1 DUF1480 family protein -
I6H01_RS02040 422924..423115 + 192 WP_001338167.1 YebW family protein -
I6H01_RS02045 423116..423772 - 657 WP_000812733.1 protein-serine/threonine phosphatase -
- 423869..424000 + 132 - - Antitoxin
- 423907..424003 - 97 - - Toxin
I6H01_RS02050 424055..424752 + 698 Protein_406 IS1-like element IS1A family transposase -
I6H01_RS02055 424952..426097 - 1146 WP_072035508.1 copper homeostasis membrane protein CopD -
I6H01_RS02060 426101..426475 - 375 WP_000168747.1 CopC domain-containing protein YobA -
I6H01_RS02065 426614..426844 + 231 WP_000916763.1 DNA polymerase III subunit theta -
I6H01_RS02070 426946..427602 + 657 WP_038340264.1 carbon-nitrogen hydrolase family protein -
I6H01_RS02075 427626..428288 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 424249..424752 503


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T183006 NZ_CP065613:c424003-423907 [Escherichia coli]
CACCTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACAGGAATC
GTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 132 bp

>AT183006 NZ_CP065613:423869-424000 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References