Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 41879..42113 | Replicon | chromosome |
| Accession | NZ_CP065607 | ||
| Organism | Escherichia coli strain FDAARGOS_946 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 41880..41983 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 41879..42113 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6H03_RS00720 | 38827..39879 | + | 1053 | WP_001004419.1 | recombinase RecT | - |
| I6H03_RS00725 | 39943..40137 | + | 195 | WP_071780718.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| I6H03_RS00730 | 40130..40318 | + | 189 | WP_001417978.1 | DUF1187 family protein | - |
| - | 40136..40314 | - | 179 | NuclAT_1 | - | - |
| - | 40136..40314 | - | 179 | NuclAT_1 | - | - |
| - | 40136..40314 | - | 179 | NuclAT_1 | - | - |
| - | 40136..40314 | - | 179 | NuclAT_1 | - | - |
| I6H03_RS00735 | 40425..40706 | + | 282 | WP_001311878.1 | excisionase | - |
| I6H03_RS00740 | 40672..41748 | + | 1077 | WP_001189085.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 41879..42113 | + | 235 | - | - | Antitoxin |
| - | 41880..41983 | - | 104 | - | - | Toxin |
| I6H03_RS00745 | 42141..42482 | - | 342 | WP_000976483.1 | YebY family protein | - |
| I6H03_RS00750 | 42495..43367 | - | 873 | WP_000879314.1 | copper homeostasis membrane protein CopD | - |
| I6H03_RS00755 | 43371..43745 | - | 375 | WP_000168751.1 | CopC domain-containing protein YobA | - |
| I6H03_RS00760 | 43884..44114 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| I6H03_RS00765 | 44216..44872 | + | 657 | WP_000011661.1 | carbon-nitrogen hydrolase family protein | - |
| I6H03_RS00770 | 44896..45558 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 89..49523 | 49434 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T182947 NZ_CP065607:c41983-41880 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT182947 NZ_CP065607:41879-42113 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
