Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3393097..3393242 Replicon chromosome
Accession NZ_CP065347
Organism Klebsiella pneumoniae strain ZG2017CW4-4-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3393104..3393206 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3393097..3393242 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5I21_RS16650 3388629..3390062 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I5I21_RS16655 3390178..3390417 + 240 WP_002911393.1 YebV family protein -
I5I21_RS16660 3390515..3390706 + 192 WP_002911395.1 YebW family protein -
I5I21_RS16665 3390703..3391356 - 654 WP_014343242.1 protein-serine/threonine phosphatase -
I5I21_RS16670 3391513..3392481 + 969 WP_004151446.1 VirK/YbjX family protein -
I5I21_RS16675 3392586..3392729 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3393097..3393242 + 146 - - Antitoxin
- 3393104..3393206 - 103 - - Toxin
I5I21_RS16680 3393365..3393703 - 339 WP_002911404.1 YebY family protein -
I5I21_RS16685 3393720..3394589 - 870 WP_014343243.1 copper homeostasis membrane protein CopD -
I5I21_RS16690 3394593..3394967 - 375 WP_014343244.1 CopC domain-containing protein YobA -
I5I21_RS16695 3395080..3395310 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I5I21_RS16700 3395389..3396048 + 660 WP_002911407.1 exodeoxyribonuclease X -
I5I21_RS16705 3396052..3398112 - 2061 WP_019705169.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182411 NZ_CP065347:c3393206-3393104 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182411 NZ_CP065347:3393097-3393242 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References