Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3393074..3393219 Replicon chromosome
Accession NZ_CP065343
Organism Klebsiella pneumoniae strain ZG2017CW4-4-1-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3393081..3393183 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3393074..3393219 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I5Q75_RS16660 3388606..3390039 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I5Q75_RS16665 3390155..3390394 + 240 WP_002911393.1 YebV family protein -
I5Q75_RS16670 3390492..3390683 + 192 WP_002911395.1 YebW family protein -
I5Q75_RS16675 3390680..3391333 - 654 WP_014343242.1 protein-serine/threonine phosphatase -
I5Q75_RS16680 3391490..3392458 + 969 WP_004151446.1 VirK/YbjX family protein -
I5Q75_RS16685 3392563..3392706 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3393074..3393219 + 146 - - Antitoxin
- 3393081..3393183 - 103 - - Toxin
I5Q75_RS16690 3393342..3393680 - 339 WP_002911404.1 YebY family protein -
I5Q75_RS16695 3393697..3394566 - 870 WP_014343243.1 copper homeostasis membrane protein CopD -
I5Q75_RS16700 3394570..3394944 - 375 WP_014343244.1 CopC domain-containing protein YobA -
I5Q75_RS16705 3395057..3395287 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I5Q75_RS16710 3395366..3396025 + 660 WP_002911407.1 exodeoxyribonuclease X -
I5Q75_RS16715 3396029..3398089 - 2061 WP_019705169.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T182392 NZ_CP065343:c3393183-3393081 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT182392 NZ_CP065343:3393074-3393219 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References