Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3393074..3393219 | Replicon | chromosome |
| Accession | NZ_CP065343 | ||
| Organism | Klebsiella pneumoniae strain ZG2017CW4-4-1-2 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3393081..3393183 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3393074..3393219 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I5Q75_RS16660 | 3388606..3390039 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| I5Q75_RS16665 | 3390155..3390394 | + | 240 | WP_002911393.1 | YebV family protein | - |
| I5Q75_RS16670 | 3390492..3390683 | + | 192 | WP_002911395.1 | YebW family protein | - |
| I5Q75_RS16675 | 3390680..3391333 | - | 654 | WP_014343242.1 | protein-serine/threonine phosphatase | - |
| I5Q75_RS16680 | 3391490..3392458 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| I5Q75_RS16685 | 3392563..3392706 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 3393074..3393219 | + | 146 | - | - | Antitoxin |
| - | 3393081..3393183 | - | 103 | - | - | Toxin |
| I5Q75_RS16690 | 3393342..3393680 | - | 339 | WP_002911404.1 | YebY family protein | - |
| I5Q75_RS16695 | 3393697..3394566 | - | 870 | WP_014343243.1 | copper homeostasis membrane protein CopD | - |
| I5Q75_RS16700 | 3394570..3394944 | - | 375 | WP_014343244.1 | CopC domain-containing protein YobA | - |
| I5Q75_RS16705 | 3395057..3395287 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| I5Q75_RS16710 | 3395366..3396025 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| I5Q75_RS16715 | 3396029..3398089 | - | 2061 | WP_019705169.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T182392 NZ_CP065343:c3393183-3393081 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT182392 NZ_CP065343:3393074-3393219 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT