Detailed information of TA system TA181641

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 2971236..2971846
• Replicon: chromosome
• Accession: NZ_CP064692
• Organism: Bradyrhizobium sp. 191

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: IVB23_RS13640
• Protein ID: WP_247804848.1
• Coordinates: 2971571..2971846 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: IVB23_RS13635
• Protein ID: WP_247803888.1
• Coordinates: 2971236..2971574 (-)
• Length: 113 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IVB23_RS13615	2967015..2967815	-	801	WP_247804844.1	EAL domain-containing protein	-
IVB23_RS13620	2967911..2968441	-	531	Protein_2717	GGDEF domain-containing protein	-
IVB23_RS39395 (IVB23_13540)	2968837..2970246	-	1410	WP_276578586.1	GGDEF domain-containing protein	-
IVB23_RS13630 (IVB23_13545)	2970382..2970660	-	279	WP_247803887.1	hypothetical protein	-
IVB23_RS13635 (IVB23_13550)	2971236..2971574	-	339	WP_247803888.1	helix-turn-helix transcriptional regulator	Antitoxin
IVB23_RS13640 (IVB23_13555)	2971571..2971846	-	276	WP_247804848.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IVB23_RS13645 (IVB23_13560)	2972227..2972808	+	582	WP_247803889.1	hypothetical protein	-
IVB23_RS13650 (IVB23_13565)	2973193..2974257	+	1065	WP_247803844.1	IS630 family transposase	-
IVB23_RS13655 (IVB23_13570)	2975235..2975429	+	195	WP_247803890.1	hypothetical protein	-
IVB23_RS13660 (IVB23_13575)	2975542..2976628	-	1087	Protein_2725	IS5 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2965855..2991558	25703
	-	flank	IS/Tn	-	-	2973241..2974257	1016

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (2-73)

Antitoxin

• HigA2-like, helix-turn-helix domain (15-94)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10177.60 Da
• Isoelectric Point: 10.0989

>T181641 WP_247804848.1 NZ_CP064692:c2971846-2971571 [Bradyrhizobium sp. 191]
VQEGEEPIAAKALRGFGGRAIQELVDDFDSKTCRAVYTVRFAGMVYVLHAFQKKAKKGIATSQQDIEPIKSRLRDAEEHY
RARADKGGRKP

Nucleotide

• Length: 276 bp

>T181641 NZ_CP086007:c1360864-1360118 [Bacillus subtilis subsp. natto]
ATGGTTTTATTCTTTCAGATCATGGTCTGGTGCATCGTGGCCGGACTGGGGTTATACGTGTATGCCACGTGGCGTTTCGA
AGCGAAGGTCAAAGAAAAAATGTCCGCCATCCGGAAAACTTGGTATTTGCTGTTTGTTCTGGGCGCTATGGTATACTGGA
CATATGAGCCCACTTCCCTATTTACCCACTGGGAACGGTATCTCATTGTCGCAGTCAGTTTTGCTTTGATTGATGCTTTT
ATCTTCTTAAGTGCATACGTCAAAAAACTGGCCGGCAGCGAGCTTGAAACAGACACAAGAGAAATTCTTGAAGAAAACAA
CGAAATGCTCCACATGTACCTCAATCGGCTGAAAACATACCAATACCTATTGAAAAACGAACCGATCCATGTTTATTATG
GAAGTATAGATGCTTATGCTGAAGGTATTGATAAACTGCTGAAAACCTATGCTGATAAAATGAACTTAACGGCCTCTCTT
TGCCACTATTCGACACAGGCTGATAAAGACCGGTTAACCGAGCATATGGATGATCCGGCAGATGTACAAACACGGCTCGA
TCGAAAGGATGTTTATTACGACCAATACGGAAAAGTGGTTCTCATCCCCTTTACCATCGAGACACAGAACTATGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTATTTACGTCATTAACGAGCATATATGATTTGGTGCTG
CCAATTGAGGAGGAAGGTGAAGGATAA

Antitoxin

Protein

• Length: 113 a.a.
• Molecular weight: 12596.71 Da
• Isoelectric Point: 10.0936

>AT181641 WP_247803888.1 NZ_CP064692:c2971574-2971236 [Bradyrhizobium sp. 191]
MTKRKIEAYEGSGNILADLGLPNPEERLLKSSIVTELHRLIKARNLTQVKAAKLIGISQPDLSHLLRGDYSDYSAERLMK
MLTVFEQDIEIVMRPHRKAGEPGRITFKPVAA

Nucleotide

• Length: 339 bp

>AT181641 NZ_CP086007:c1360118-1359948 [Bacillus subtilis subsp. natto]
ATGGAACGTGCGTTTCAAAACAGATGCGAGCCCAGAGCGGCGAAGCCGTTTAAAATCCTGAAAAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGTCCGCATACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA