Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 839952..840612 Replicon chromosome
Accession NZ_CP064661
Organism Salmonella sp. SJTUF14178

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag IVP18_RS04105 Protein ID WP_000244755.1
Coordinates 840199..840612 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag IVP18_RS04100 Protein ID WP_000351186.1
Coordinates 839952..840218 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IVP18_RS04080 836261..836572 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
IVP18_RS04085 836736..837395 + 660 WP_000250289.1 hemolysin III family protein -
IVP18_RS04090 837653..838639 + 987 WP_023226548.1 IS110 family transposase -
IVP18_RS04095 838722..839702 - 981 WP_017441090.1 tRNA-modifying protein YgfZ -
IVP18_RS04100 839952..840218 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
IVP18_RS04105 840199..840612 + 414 WP_000244755.1 protein YgfX Toxin
IVP18_RS04110 840665..841186 - 522 WP_001055885.1 flavodoxin FldB -
IVP18_RS04115 841299..842195 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
IVP18_RS04120 842219..842932 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
IVP18_RS04125 842938..844671 + 1734 WP_023227724.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T181289 WP_000244755.1 NZ_CP064661:840199-840612 [Salmonella sp. SJTUF14178]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

>T181289 NZ_CP085817:2706856-2707011 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT181289 WP_000351186.1 NZ_CP064661:839952-840218 [Salmonella sp. SJTUF14178]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT181289 NZ_CP085817:c2706844-2706786 [Salmonella enterica subsp. enterica serovar Enteritidis]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGCAAAGCATGAAATTGGCCTCA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References