Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 518809..519080 Replicon chromosome
Accession NZ_CP064387
Organism Escherichia coli O104:H4 strain PartB-EcoliO104H4-RM8376

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 518939..519042 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 518809..519080 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUJ37_RS02515 515364..516026 - 663 WP_000944256.1 exodeoxyribonuclease X -
IUJ37_RS02520 516050..516706 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
IUJ37_RS02525 516808..517038 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IUJ37_RS02530 517177..517551 + 375 WP_000204699.1 CopC domain-containing protein YobA -
IUJ37_RS02535 517555..518427 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
IUJ37_RS02540 518440..518781 + 342 WP_000976472.1 YebY family protein -
- 518809..519080 - 272 - - Antitoxin
- 518939..519042 + 104 - - Toxin
IUJ37_RS02545 519177..519833 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
IUJ37_RS02550 519834..520025 - 192 WP_001296140.1 YebW family protein -
IUJ37_RS02555 520130..520366 - 237 WP_001295499.1 YebV family protein -
IUJ37_RS02560 520484..521923 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T181089 NZ_CP064387:518939-519042 [Escherichia coli O104:H4]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT181089 NZ_CP064387:c519080-518809 [Escherichia coli O104:H4]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References