Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2218663..2218934 Replicon chromosome
Accession NZ_CP064383
Organism Escherichia coli O157:H7 strain PartA-EcoliO157H7-RM8376

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2218701..2218804 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2218663..2218934 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUJ36_RS11555 2215820..2217259 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IUJ36_RS11560 2217377..2217613 + 237 WP_001295499.1 YebV family protein -
IUJ36_RS11565 2217718..2217909 + 192 WP_001296140.1 YebW family protein -
IUJ36_RS11570 2217910..2218566 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 2218663..2218934 + 272 - - Antitoxin
- 2218701..2218804 - 104 - - Toxin
IUJ36_RS11575 2218962..2219303 - 342 WP_000976483.1 YebY family protein -
IUJ36_RS11580 2219316..2220188 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
IUJ36_RS11585 2220192..2220566 - 375 WP_000168751.1 CopC domain-containing protein YobA -
IUJ36_RS11590 2220705..2220935 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IUJ36_RS11595 2221037..2221693 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
IUJ36_RS11600 2221717..2222379 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T181039 NZ_CP064383:c2218804-2218701 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT181039 NZ_CP064383:2218663-2218934 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References