Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2004328..2004473 Replicon chromosome
Accession NZ_CP064258
Organism Klebsiella pneumoniae strain JX-CR-hvKP-10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2004364..2004466 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2004328..2004473 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS497_RS09810 1999458..2001518 + 2061 WP_004151449.1 oligopeptidase B -
IS497_RS09815 2001522..2002181 - 660 WP_002911407.1 exodeoxyribonuclease X -
IS497_RS09820 2002260..2002490 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IS497_RS09825 2002603..2002977 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IS497_RS09830 2002981..2003850 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
IS497_RS09835 2003867..2004205 + 339 WP_002911404.1 YebY family protein -
- 2004328..2004473 - 146 - - Antitoxin
- 2004364..2004466 + 103 - - Toxin
IS497_RS09840 2004841..2004984 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IS497_RS09845 2005089..2006057 - 969 WP_004151446.1 VirK/YbjX family protein -
IS497_RS09850 2006214..2006867 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
IS497_RS09855 2006864..2007055 - 192 WP_002911395.1 YebW family protein -
IS497_RS09860 2007153..2007392 - 240 WP_002911393.1 YebV family protein -
IS497_RS09865 2007508..2008941 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T180759 NZ_CP064258:2004364-2004466 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT180759 NZ_CP064258:c2004473-2004328 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References