Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2067993..2068138 Replicon chromosome
Accession NZ_CP064246
Organism Klebsiella pneumoniae strain JX-CR-hvKP-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2068029..2068131 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2067993..2068138 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS498_RS10200 2063123..2065183 + 2061 WP_004151449.1 oligopeptidase B -
IS498_RS10205 2065187..2065846 - 660 WP_002911407.1 exodeoxyribonuclease X -
IS498_RS10210 2065925..2066155 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IS498_RS10215 2066268..2066642 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IS498_RS10220 2066646..2067515 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
IS498_RS10225 2067532..2067870 + 339 WP_002911404.1 YebY family protein -
- 2067993..2068138 - 146 - - Antitoxin
- 2068029..2068131 + 103 - - Toxin
IS498_RS10230 2068506..2068649 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IS498_RS10235 2068754..2069722 - 969 WP_004151446.1 VirK/YbjX family protein -
IS498_RS10240 2069879..2070532 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
IS498_RS10245 2070529..2070720 - 192 WP_002911395.1 YebW family protein -
IS498_RS10250 2070818..2071057 - 240 WP_002911393.1 YebV family protein -
IS498_RS10255 2071173..2072606 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T180702 NZ_CP064246:2068029-2068131 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT180702 NZ_CP064246:c2068138-2067993 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References